Prednisone is EXTREMELY dangerous and can cause many systematic problems which can be quickly fatal - heart attack, shock, etc… NEVER skip or alter the dosages in any way unless told to do so by the doctor. I had the same issue as you - Started out on a high dosage, but the hearing loss came back when I got down to the lower end of the taper. The doctor gave me a refill and had me run the entire course again (including the taper). You cannot stay on a high dosage of prednisone for a long period of time. There are many very bad issues like severe bone loss, glaucoma, liver and heart problems to name a few.